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Carcinoma in situ of the left lateral surface of the tongue. The lesion is a mixed erythematous and white plaque. |
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In this example there are disorderly, hyperchromatic squamous cells throughout the thickness of the epithelium. |
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The arrows point to atypical, multipolar mitotic figures; these are commonly seen in both CA-in-situ and invasive SqCA. We speak of CA-in-situ when the dysplastic keratinocytes remain localized within the epithium. |
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